Identification and evaluation of fragmentation pathways of PDE-5 inhibitor analogues using LC-QTOF-MS
نویسندگان
چکیده
منابع مشابه
hazard evaluation of gas condensate stabilization and dehydration unit of parsian gas refinery using hazop procedures
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The inner medullary collecting duct (IMCD) is an important site of vasopressin-regulated water and urea transport. Here we have used protein mass spectrometry to investigate the proteome of the IMCD cell and how it is altered in response to long-term vasopressin administration in rats. IMCDs were isolated from inner medullas of rats, and IMCD proteins were identified by liquid chromatography/ta...
متن کاملSelective separation, detection of zotepine and mass spectral characterization of degradants by LC–MS/MS/QTOF
A simple, precise, accurate stability-indicating gradient reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed for the quantitative determination of zotepine (ZTP) in bulk and pharmaceutical dosage forms in the presence of its degradation products (DPs). The method was developed using Phenomenex C18 column (250 mm×4.6 mm i.d., 5 µm) with a mobile phase containin...
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ژورنال
عنوان ژورنال: Analytical Science and Technology
سال: 2015
ISSN: 1225-0163
DOI: 10.5806/ast.2015.28.4.278